SCHEMBL9736659

SCHEMBL9736659

Nc1ccc(Oc2ccc(C(c3ccc(Oc4ccc(N)c(C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c4)cc3)(C(F)(F)F)C(F)(F)F)cc2)cc1C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.37
L3MBTL1 Q9Y468 3/20 0.35
RAB9A P51151 2/20 0.35
MAPT P10636 4/20 0.33
LMNA P02545 1/20 0.33
ATM Q13315 1/20 0.33
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32
AR P10275 2/20 0.31
MEN1 O00255 1/20 0.31
MITF O75030 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9735774 0.99 NR4A1 (0.36) NR4A1L3MBTL1RAB9AMAPTLMNA
SCHEMBL9737990 0.99 NR4A1 (0.36) NR4A1L3MBTL1RAB9AMAPTLMNA
SCHEMBL10413667 0.89 NR4A1 (0.37) NR4A1L3MBTL1RAB9AMAPTLMNA
SCHEMBL30287650 0.85 NR4A1 (0.41) NR4A1L3MBTL1RAB9AMAPTLMNA
SCHEMBL649033 0.85 NR4A1 (0.41) NR4A1L3MBTL1RAB9AMAPTLMNA
SCHEMBL10415054 0.84 NR4A1 (0.38) NR4A1L3MBTL1RAB9AMAPTLMNA
SCHEMBL10413638 0.81 RAB9A (0.36) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL7866557 0.80 NR4A1 (0.61) NR4A1L3MBTL1RAB9AMAPTLMNA
SCHEMBL8762359 0.79 L3MBTL1 (0.37) NR4A1L3MBTL1RAB9AMAPTLMNA
SCHEMBL9736024 0.78 L3MBTL1 (0.39) L3MBTL1RAB9AMAPTLMNAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5089628-A Heat resistance, moisture resistance, low dielectric constants CENTRAL GLASS COMPANY, LIMITED (JP) 1992-02-18 US disclosed