Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.51 |
| ▸ | RXRB | P28702 | 3/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lifibrol SCHEMBL9478310 | 0.90 | NR4A2 (0.64) | RXRARXRBNR4A2PLA2G4BPOLB | |
| Lifibrol SCHEMBL140583 | 0.90 | NR4A2 (0.64) | RXRARXRBNR4A2PLA2G4BPOLB | |
| Lifibrol SCHEMBL9484778 | 0.90 | NR4A2 (0.64) | RXRARXRBNR4A2PLA2G4BPOLB | |
| SCHEMBL9384511 | 0.81 | PLA2G4B (0.48) | RXRARXRBNR4A2PLA2G4BPOLB | |
| SCHEMBL9738348 | 0.81 | GAA (0.49) | LMNAMAPTCA12CA1CA2 | |
| SCHEMBL24464736 | 0.79 | RXRA (0.78) | RXRARXRBNR4A2PLA2G4BPOLB | |
| SCHEMBL9485011 | 0.79 | CA1 (0.52) | RXRARXRBNR4A2LMNAMAPT | |
| SCHEMBL10820832 | 0.79 | CA1 (0.52) | RXRARXRBNR4A2LMNAMAPT | |
| Terbufibrol SCHEMBL2733943 | 0.78 | NR4A2 (0.67) | RXRARXRBNR4A2PLA2G4BPOLB | |
| SCHEMBL10820851 | 0.77 | NR1H4 (0.58) | RXRARXRBNR4A2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153353-A | Antilipemic agents | KLINGE PHARMA GMBH (DE) | 1992-10-06 | — | — | US | disclosed |