Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.46 |
| ▸ | BRS3 | P32247 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10820832 | 0.90 | CA1 (0.52) | GAATSHRALDH1A1LMNAADRB2 | |
| SCHEMBL9485011 | 0.90 | CA1 (0.52) | GAATSHRALDH1A1LMNAADRB2 | |
| SCHEMBL9736669 | 0.81 | RXRA (0.51) | LMNAADRB2ADRB3ADRB1MAPT | |
| SCHEMBL28335565 | 0.78 | LMNA (0.69) | GAATSHRALDH1A1LMNAMAPT | |
| Lifibrol SCHEMBL140583 | 0.78 | NR4A2 (0.64) | GAAALDH1A1LMNAMAPTMEN1 | |
| Lifibrol SCHEMBL9484778 | 0.78 | NR4A2 (0.64) | GAAALDH1A1LMNAMAPTMEN1 | |
| Lifibrol SCHEMBL9478310 | 0.78 | NR4A2 (0.64) | GAAALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9660242 | 0.77 | AR (0.46) | GAAALDH1A1LMNAADRB2ADRB3 | |
| SCHEMBL6656906 | 0.76 | CYP4A11 (0.62) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL9129171 | 0.76 | CA1 (0.53) | TSHRALDH1A1MAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153353-A | Antilipemic agents | KLINGE PHARMA GMBH (DE) | 1992-10-06 | — | — | US | disclosed |