Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736693 | 1.00 | KDM4E (0.48) | KDM4EMAPTHPGDSMN1; SMN2P2RY12 | |
| SCHEMBL12127246 | 0.78 | NPC1 (0.46) | KDM4EMAPTP2RY12MDM2NPC1 | |
| SCHEMBL12127241 | 0.78 | NPC1 (0.46) | KDM4EMAPTP2RY12MDM2NPC1 | |
| SCHEMBL4830244 | 0.77 | MAPK14 (0.65) | MAPK14 | |
| SCHEMBL4563558 | 0.74 | KDM4E (0.44) | KDM4EMAPTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL30613284 | 0.73 | NPC1 (0.51) | KDM4EMAPTHPGDP2RY12NPC1 | |
| SCHEMBL11838994 | 0.73 | LMNA (0.59) | KDM4EHPGDSMN1; SMN2MDM2MEN1 | |
| SCHEMBL14176238 | 0.72 | TARBP2 (0.57) | KDM4EMAPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL4752151 | 0.71 | CA12 (0.69) | NPC1RAB9A | |
| SCHEMBL4752149 | 0.71 | CA12 (0.69) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005148-A1 | IMIDAZOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATIONS | RHONE-POULENC RORER LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |