Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 11/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 11/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6007986 | 0.89 | AGTR1 (0.54) | AGTR1AGTR2PPARG | |
| SCHEMBL9528345 | 0.87 | FOLH1 (0.42) | FOLH1AGTR1AGTR2LTB4RLTB4R2 | |
| SCHEMBL6006042 | 0.80 | AGTR1 (0.53) | AGTR1AGTR2PPARG | |
| SCHEMBL6005713 | 0.78 | AGTR1 (0.54) | AGTR1AGTR2PPARG | |
| SCHEMBL6007812 | 0.78 | AGTR1 (0.53) | AGTR1AGTR2PPARG | |
| SCHEMBL9428342 | 0.77 | FOLH1 (0.41) | FOLH1AGTR1AGTR2LTB4RLTB4R2 | |
| SCHEMBL6005884 | 0.76 | AGTR1 (0.52) | AGTR1AGTR2PPARG | |
| SCHEMBL6007042 | 0.76 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL6006071 | 0.76 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL6006926 | 0.76 | AGTR1 (0.52) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004335-A2 | RENAL-SELECTIVE BIPHENYLALKYL 1H-SUBSTITUTED-1,2,4-TRIAZOLE ANGIOTENSIN II ANTAGONISTS FOR TREATMENT OF HYPERTENSION | G.D. SEARLE & CO. (US) | 1992-03-19 | — | — | WO | disclosed |