Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.37 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.35 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9455354 | 0.91 | PPARG (0.44) | AGTR1AGTR2 | |
| SCHEMBL9427972 | 0.79 | PPARG (0.57) | AGTR1AGTR2 | |
| SCHEMBL7049483 | 0.77 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9429451 | 0.77 | SLC6A3 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9736713 | 0.77 | FOLH1 (0.44) | FOLH1LTB4RLTB4R2AGTR1AGTR2 | |
| SCHEMBL9428161 | 0.74 | SLC16A3 (0.35) | SLC16A3MCTS1SLC16A1 | |
| SCHEMBL9528345 | 0.74 | FOLH1 (0.42) | FOLH1LTB4RLTB4R2AGTR1AGTR2 | |
| SCHEMBL10514075 | 0.74 | PPARG (0.50) | FOLH1AGTR1AGTR2 | |
| SCHEMBL9427421 | 0.73 | PPARG (0.54) | AGTR1AGTR2 | |
| SCHEMBL9428006 | 0.72 | AGTR1 (0.49) | LTB4R2AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5315013-A | Hypotensive | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-05-24 | — | — | US | disclosed |