Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.69 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5988415 | 0.82 | ACHE (1.00) | ACHEAPPBCHE | |
| SCHEMBL10653085 | 0.79 | ACHE (0.63) | ACHEBCHEALDH1A1 | |
| SCHEMBL10651068 | 0.79 | ACHE (0.63) | ACHEBCHE | |
| SCHEMBL10654149 | 0.79 | ACHE (0.65) | ACHEBCHETDP1 | |
| SCHEMBL9875274 | 0.79 | ACHE (0.67) | ACHEAPPBCHE | |
| SCHEMBL9172013 | 0.75 | ACHE (0.66) | ACHEBCHEALDH1A1CYP3A4TSHR | |
| SCHEMBL9209834 | 0.75 | ACHE (0.59) | ACHEAPPBCHEALDH1A1TDP1 | |
| SCHEMBL10651833 | 0.72 | ACHE (0.41) | ACHEBCHE | |
| SCHEMBL10990085 | 0.71 | ACHE (0.61) | ACHEAPPBCHE | |
| SCHEMBL9748628 | 0.71 | ACHE (1.00) | ACHEAPPBCHEALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112830-A | Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-05-12 | — | — | US | claimed |
| US-5130386-A | Reaction vessel with a coating of tannin and polymer on the interior and drying | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-07-14 | — | — | US | disclosed |