Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 12/20 | 0.71 |
| ▸ | MAPK12 | P53778 | 12/20 | 0.71 |
| ▸ | MAPK11 | Q15759 | 12/20 | 0.71 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.71 |
| ▸ | RAF1 | P04049 | 6/20 | 0.71 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.71 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | GCGR | P47871 | 5/20 | 0.60 |
| ▸ | BRAF | P15056 | 3/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LDHA | P00338 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15075610 | 0.88 | MAPK13 (0.77) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL28399057 | 0.87 | MAPK13 (0.76) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL28398004 | 0.85 | MAPK13 (0.77) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL15075608 | 0.84 | MAPK13 (0.72) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL28400755 | 0.84 | BRAF (0.58) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL15075635 | 0.84 | MAPK14 (0.78) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL104130 | 0.84 | MAPK13 (0.82) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| Benzene SCHEMBL28852698 | 0.84 | MAPK13 (0.82) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL15075609 | 0.83 | SMPD3 (0.67) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL2949385 | 0.83 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111057043-A | Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method | 深圳市贝加电子材料有限公司 | 2020-04-24 | — | — | CN | claimed |
| WO-1992005148-A1 | IMIDAZOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATIONS | RHONE-POULENC RORER LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |