Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736566 | 1.00 | EHMT2 (0.41) | EHMT2BRD4KMT2AMEN1KDM4E | |
| SCHEMBL9737467 | 0.81 | EHMT2 (0.35) | EHMT2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL11174084 | 0.80 | EHMT2 (0.47) | EHMT2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL11174081 | 0.80 | EHMT2 (0.47) | EHMT2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL11174075 | 0.80 | EHMT2 (0.47) | EHMT2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL351271 | 0.80 | EHMT2 (0.56) | EHMT2BRD4KMT2AMEN1POLB | |
| SCHEMBL22130803 | 0.80 | EHMT2 (0.56) | EHMT2BRD4KMT2AMEN1POLB | |
| SCHEMBL353717 | 0.80 | EHMT2 (0.56) | EHMT2BRD4KMT2AMEN1POLB | |
| SCHEMBL9679741 | 0.79 | EHMT2 (0.46) | EHMT2BRD4KMT2AMEN1POLB | |
| SCHEMBL3084318 | 0.79 | EHMT2 (0.46) | EHMT2BRD4KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095118-A | PROCESS FOR THE PREPARATION OF D-(+)-BIOTIN | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-03-10 | — | — | US | disclosed |
| US-4937351-A | Process for the preparation of D-(+)-biotin | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-06-26 | — | — | US | disclosed |
| US-4877882-A | Process for the preparation of D-(+)-biotin | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-10-31 | — | — | US | disclosed |
| US-4837402-A | Process for the preparation of D-(+)-biotin | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-06-06 | — | — | US | disclosed |
| US-4732987-A | Process for the preparation of D-(+)-biotin | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-03-22 | — | — | US | disclosed |