Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | POLA1 | P09884 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10667584 | 0.85 | EHMT2 (0.38) | EHMT2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL9679059 | 0.85 | EHMT2 (0.38) | EHMT2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL9736566 | 0.81 | EHMT2 (0.41) | EHMT2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL9736877 | 0.81 | EHMT2 (0.41) | EHMT2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL9845295 | 0.73 | MEN1 (0.42) | EHMT2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL9032586 | 0.73 | MEN1 (0.42) | EHMT2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL9679618 | 0.72 | EHMT2 (0.42) | EHMT2KDM4EMEN1KMT2APOLB | |
| SCHEMBL9845296 | 0.71 | MEN1 (0.39) | EHMT2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL6049147 | 0.67 | ALDH1A1 (0.53) | EHMT2MEN1KMT2APOLBPOLA1 | |
| SCHEMBL9031247 | 0.67 | ALDH1A1 (0.53) | EHMT2MEN1KMT2APOLBPOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095118-A | PROCESS FOR THE PREPARATION OF D-(+)-BIOTIN | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-03-10 | — | — | US | disclosed |
| US-4937351-A | Process for the preparation of D-(+)-biotin | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-06-26 | — | — | US | disclosed |
| US-4877882-A | Process for the preparation of D-(+)-biotin | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-10-31 | — | — | US | disclosed |