Sugi Predict

Sugi Predict / Compounds / SCHEMBL353717

SCHEMBL353717

SCHEMBL353717

O=C(O)[C@@H]1[C@H](C(=O)O)N(Cc2ccccc2)C(=O)N1Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EHMT2 Q96KQ7 1/20 0.56
▸ F2 P00734 1/20 0.50
▸ PLG P00747 1/20 0.50
▸ ELANE P08246 1/20 0.50
▸ CTSG P08311 1/20 0.50
▸ CMA1 P23946 1/20 0.50
▸ CTRC Q99895 1/20 0.50
▸ KMT2A Q03164 3/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ EP300 Q09472 2/20 0.46
▸ CYP2C19 P33261 3/20 0.45
▸ CYP2C9 P11712 2/20 0.45
▸ POLB P06746 1/20 0.45
▸ CYP2D6 P10635 1/20 0.45
▸ S1PR1 P21453 1/20 0.44
▸ S1PR5 Q9H228 1/20 0.44
▸ CYP3A4 P08684 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ GSK3A P49840 1/20 0.42
▸ GSK3B P49841 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22130803 1.00 EHMT2 (0.56) EHMT2F2PLGELANECTSG
SCHEMBL351271 1.00 EHMT2 (0.56) EHMT2F2PLGELANECTSG
SCHEMBL10956698 0.93 EHMT2 (0.50) EHMT2F2PLGELANECTSG
SCHEMBL5082176 0.90 EHMT2 (0.47) EHMT2F2PLGELANECTSG
SCHEMBL10721577 0.87 ALDH1A1 (0.50) EHMT2KMT2AMEN1POLB
SCHEMBL9032781 0.87 ALDH1A1 (0.50) EHMT2KMT2AMEN1POLB
SCHEMBL9030364 0.87 ALDH1A1 (0.50) EHMT2KMT2AMEN1POLB
SCHEMBL11177434 0.87 ALDH1A1 (0.50) EHMT2KMT2AMEN1POLB
SCHEMBL11199133 0.87 ALDH1A1 (0.50) EHMT2KMT2AMEN1POLB
SCHEMBL9030374 0.87 ALDH1A1 (0.50) EHMT2KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199653-A1 METHOD FOR FORMING AN ELECTRICALLY CONDUCTIVE METAL ORGANIC FRAMEWORK COMPOSITE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-06-20 — — US claimed
EP-3801880-A1 METHOD FOR IN-SITU SYNTHESIS OF METAL ORGANIC FRAMEWORKS (MOFS), COVALENT ORGANIC FRAMEWORKS (COFS) AND ZEOLITE IMIDAZOLATE FRAMEWORKS (ZIFS), AND APPLICATIONS THEREOF Desiccant Rotors International Private Ltd. (IN) 2021-04-14 — — EP claimed
US-20210016245-A1 METHOD FOR IN-SITU SYNTHESIS OF METAL ORGANIC FRAMEWORKS (MOFs), COVALENT ORGANIC FRAMEWORKS (COFs) AND ZEOLITE IMIDAZOLATE FRAMEWORKS (ZIFs), AND APPLICATIONS THEREOF DESICCANT ROTORS INTERNATIONAL PRIVATE LIMITED (IN) 2021-01-21 — — US claimed
US-20200291045-A1 CONDUCTIVITY ENHANCEMENT OF MOFS VIA DEVELOPMENT OF MOFPOLYMER COMPOSITE MATERIAL KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2020-09-17 — — US claimed
EP-2739169-B1 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS MASSACHUSETTS INST TECHNOLOGY (US) 2019-06-12 — — EP claimed
US-20140311507-A1 Porous Catalytic Matrices for Elimination of Toxicants Found in Tobacco Combustion Products MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-10-23 — — US claimed
EP-2739169-A2 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS Massachusetts Institute Of Technology (US) 2014-06-11 — — EP claimed
WO-2013019865-A2 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-02-07 — — WO claimed
EP-1127879-B1 Preparation of 2-oxo-1,3-dibenzyl-cis-4,5-imidazolidin dicarboxylic acid and its anhydrid DSM IP ASSETS BV (NL) 2005-05-25 — — EP claimed
US-6344565-B1 REACTION OF BIS(BENZYLAMINO)SUCCINIC ACID DIALKALI METAL SALT WITH TRIPHOSGENE, ACIDIFICATION IN WATER ROCHE VITAMINS, INC. 2002-02-05 — — US claimed
US-6291681-B1 REACTING MESO-2,3-BIS(BENZYLAMINO)SUCCINIC ACID DIALKALI METAL SALT WITH PHENYL CHLOROFORMATE; ACIDIFICATION, ISOLATING 2-OXO-1,3-DIBENZYL-CIS-4,5-IMIDAZOLIDINEDICARBOXYLIC ACID; HEATING WITH ACETIC ANHYDRIDE TO PRODUCE ANHYDRIDE COMPOUND ROCHE VITAMINS INC. 2001-09-18 — — US claimed
US-20010020101-A1 Process for preparing biotin F. HOFFMANN-LA ROCHE AG 2001-09-06 — — US claimed
US-5151525-A Process for producing 2-oxo-1,3-dibenzyl-4,5-cis-imidazolidinedicarboxylic acid PPG INDUSTRIES, INC. (US) 1992-09-29 — — US claimed
EP-0044158-B1 NOVEL OPTICALLY ACTIVE IMIDAZOLIDIN-2-ONE DERIVATIVES AND THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-08-15 — — EP claimed
EP-0044158-A1 Novel optically active imidazolidin-2-one derivatives and their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-01-20 — — EP claimed
JP-55102570-A — — None — — JP disclosed
JP-59059668-A — — None — — JP disclosed
EP-0044158-A1 Novel optically active imidazolidin-2-one derivatives and their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-01-20 — — EP disclosed
JP-S55102570-A ISOLATION OF CIS-1,3-DIBENZYL-2-OXO-IMIDAZOLIDINE-4,5- DICARBOXYLIC ACID SUMITOMO CHEM CO LTD 1980-08-05 — — JP disclosed
US-4014895-A Method for synthesis of optically active thiolactones SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-03-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010020101-A1 Process for preparing biotin OGDH, BTD, DDC EHMT2 1403/4885F2 1670/4885PLG 1685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.