Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735904 | 1.00 | RAB9A (0.41) | RAB9AKMT2ANPC1SOAT1MEN1 | |
| SCHEMBL9736852 | 0.76 | HSD11B1 (0.39) | ALDH1A1HSD11B1 | |
| SCHEMBL9737366 | 0.76 | HSD11B1 (0.39) | ALDH1A1HSD11B1 | |
| SCHEMBL8871197 | 0.74 | RAB9A (0.44) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL8614296 | 0.74 | RAB9A (0.44) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL8614303 | 0.74 | RAB9A (0.44) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL9736381 | 0.72 | NPSR1 (0.35) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL9736590 | 0.72 | NPSR1 (0.35) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL10378727 | 0.72 | NPSR1 (0.35) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL10378318 | 0.71 | NPSR1 (0.35) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138050-A | 6-amido-1-methyl carbapenems | MERCK & CO., INC. (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1990000170-A1 | NOVEL 6-AMIDO-1-METHYLCARBAPENEMS | MERCK & CO., INC. (US) | 1990-01-11 | — | — | WO | disclosed |
| EP-0350211-A2 | Novel 6-amido-1-methyl carbapenems | MERCK & CO. INC. (US) | 1990-01-10 | — | — | EP | disclosed |