Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | TLR3 | O15455 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL612838 | 0.82 | KIT (0.59) | KITMAPTKDM4EMEN1NR3C1 | |
| SCHEMBL2311050 | 0.82 | KIT (0.49) | KITMAPTKDM4EMEN1NR3C1 | |
| SCHEMBL2313733 | 0.82 | MAPT (0.49) | KITMAPTKDM4EMEN1NR3C1 | |
| SCHEMBL9738319 | 0.76 | MAPT (0.56) | MAPTACHECHUKMAOABRD4 | |
| SCHEMBL613815 | 0.74 | MAOA (0.54) | KITMAPTKDM4ENPSR1ALDH1A1 | |
| SCHEMBL2311605 | 0.72 | KIT (0.54) | KITMAPTKDM4EMEN1NR3C1 | |
| SCHEMBL2308791 | 0.71 | KIT (0.55) | KITMAPTKDM4EMEN1NR3C1 | |
| SCHEMBL2311857 | 0.71 | KIT (0.65) | KITMAPTKDM4EMEN1NR3C1 | |
| SCHEMBL2308783 | 0.71 | KIT (0.59) | KITMAPTKDM4EMEN1NR3C1 | |
| SCHEMBL24276887 | 0.70 | KIT (0.67) | KITMAPTKDM4EMEN1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079363-A | From an alkoxypyridine and an indole derivative, antitumor and antileukemia agents | SANOFI (FR) | 1992-01-07 | — | — | US | disclosed |