Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.53 |
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.40 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.40 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.40 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.40 |
| ▸ | CBFB | Q13951 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874880 | 0.78 | KDM4E (0.55) | ACHEBCHEAPPELANEMEN1 | |
| SCHEMBL13697268 | 0.77 | KMT2A (0.61) | ACHEBCHEAPPELANEMEN1 | |
| SCHEMBL13696892 | 0.72 | KMT2A (0.55) | ACHEBCHEAPPELANEMEN1 | |
| SCHEMBL9169032 | 0.72 | ACHE (0.60) | ACHEBCHEAPPRAB9AKDM4E | |
| SCHEMBL9173536 | 0.72 | ACHE (0.47) | ACHEBCHEAPPELANEMEN1 | |
| SCHEMBL9173459 | 0.72 | ACHE (0.53) | ACHEBCHEAPPMEN1KMT2A | |
| SCHEMBL4163110 | 0.71 | KMT2A (0.66) | ACHEMEN1KMT2AMAPTNPC1 | |
| SCHEMBL13697360 | 0.69 | ABCG2 (0.55) | ACHEMEN1KMT2AMAPTNPC1 | |
| SCHEMBL7763069 | 0.67 | GNG2 (0.81) | MEN1KMT2AMAPTNPSR1MMP1 | |
| SCHEMBL4163695 | 0.66 | KDM4E (0.65) | ELANEMEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112830-A | Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-05-12 | — | — | US | claimed |