Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736947 | 0.95 | HIF1A (0.39) | TYMPKDM4EHIF1AEPAS1ALDH1A1 | |
| SCHEMBL9737372 | 0.93 | HIF1A (0.41) | TYMPKDM4EHIF1AEPAS1ALDH1A1 | |
| SCHEMBL9736441 | 0.93 | HIF1A (0.41) | TYMPKDM4EHIF1AEPAS1ALDH1A1 | |
| SCHEMBL9736823 | 0.77 | IGF1R (0.32) | — | |
| SCHEMBL25255954 | 0.66 | ALDH1A1 (0.54) | KDM4EALDH1A1MAPK1MAPTHTT | |
| SCHEMBL25300724 | 0.66 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPK1MAPTHTT | |
| SCHEMBL27043102 | 0.66 | HCAR2 (0.37) | TYMPKDM4EPKMALDH1A1 | |
| SCHEMBL18825085 | 0.66 | HIF1A (0.41) | TYMPKDM4EHIF1AEPAS1ALDH1A1 | |
| SCHEMBL16328687 | 0.64 | KDM4E (0.44) | KDM4EPKMHIF1AEPAS1MAPT | |
| SCHEMBL17949542 | 0.64 | ALDH1A1 (0.41) | ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132101-A | Acetylene-cumulene porphycene compounds for photodynamic therapy | CYTOPHARM, INC. (US) | 1992-07-21 | — | — | US | disclosed |