Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 4/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736441 | 0.98 | HIF1A (0.41) | HIF1AEPAS1TYMPGPR84MAPT | |
| SCHEMBL9737372 | 0.98 | HIF1A (0.41) | HIF1AEPAS1TYMPGPR84MAPT | |
| SCHEMBL9737200 | 0.95 | TYMP (0.35) | HIF1AEPAS1TYMPMAPTKDM4E | |
| SCHEMBL9736823 | 0.76 | IGF1R (0.32) | — | |
| SCHEMBL18825085 | 0.71 | HIF1A (0.41) | HIF1AEPAS1TYMPGPR84KDM4E | |
| SCHEMBL6427930 | 0.69 | SCD (0.40) | GPR84ALDH1A1HSD17B10 | |
| SCHEMBL10885262 | 0.64 | GPR84 (0.42) | HIF1AEPAS1TYMPGPR84 | |
| SCHEMBL10716857 | 0.63 | HIF1A (0.43) | HIF1AEPAS1TYMPGPR84MAPT | |
| SCHEMBL9766749 | 0.63 | HIF1A (0.44) | HIF1AEPAS1GPR84MAPT | |
| SCHEMBL9766716 | 0.62 | HIF1A (0.46) | HIF1AEPAS1GPR84MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132101-A | Acetylene-cumulene porphycene compounds for photodynamic therapy | CYTOPHARM, INC. (US) | 1992-07-21 | — | — | US | disclosed |