Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP9 | P55211 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28237669 | 0.90 | CYP4F2 (0.52) | SMN1; SMN2ABCB1TSHRCYP4F2CYP4A11 | |
| SCHEMBL9374658 | 0.87 | TSHR (0.70) | SMN1; SMN2ABCB1TSHRCYP4F2CYP4A11 | |
| Phthalic Acid SCHEMBL28439156 | 0.86 | TSHR (0.53) | SMN1; SMN2ABCB1TSHRCYP4F2CYP4A11 | |
| SCHEMBL32688037 | 0.85 | TSHR (0.52) | ABCB1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL3949459 | 0.85 | CTNNB1 (0.54) | SMN1; SMN2ABCB1TSHRCYP4F2CYP4A11 | |
| SCHEMBL9348474 | 0.83 | TSHR (0.50) | SMN1; SMN2ABCB1TSHRCYP4F2CYP4A11 | |
| SCHEMBL13962647 | 0.83 | CYP4F2 (0.55) | SMN1; SMN2ABCB1TSHRCYP4F2CYP4A11 | |
| SCHEMBL9635632 | 0.83 | MEN1 (0.50) | SMN1; SMN2ABCB1TSHRCYP4F2CYP4A11 | |
| SCHEMBL15778916 | 0.82 | TSHR (0.49) | SMN1; SMN2ABCB1TSHRCYP4F2CYP4A11 | |
| SCHEMBL31520096 | 0.82 | ALDH1A1 (0.63) | SMN1; SMN2ABCB1TSHRCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093495-A | Benzoheterocyclic compounds | SHELL OIL COMPANY (US) | 1992-03-03 | — | — | US | disclosed |