Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 8/20 | 0.54 |
| ▸ | WNT3A | P56704 | 8/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30089517 | 0.85 | CTNNB1 (0.68) | CTNNB1WNT3AERCC5FEN1MEN1 | |
| SCHEMBL15979740 | 0.85 | CTNNB1 (0.68) | CTNNB1WNT3AERCC5FEN1MEN1 | |
| SCHEMBL13962647 | 0.85 | CYP4F2 (0.55) | TSHRSMN1; SMN2ABCB1CYP4F2CYP4A11 | |
| SCHEMBL9348474 | 0.85 | TSHR (0.50) | CTNNB1TSHRSMN1; SMN2ABCB1CYP4F2 | |
| SCHEMBL9737218 | 0.85 | SMN1; SMN2 (0.53) | TSHRSMN1; SMN2ABCB1CYP4F2CYP4A11 | |
| SCHEMBL9374658 | 0.85 | TSHR (0.70) | TSHRSMN1; SMN2ABCB1CYP4F2CYP4A11 | |
| SCHEMBL406193 | 0.84 | ERCC5 (0.59) | TSHRSMN1; SMN2ERCC5FEN1MEN1 | |
| SCHEMBL15778916 | 0.83 | TSHR (0.49) | TSHRSMN1; SMN2ABCB1CYP4F2CYP4A11 | |
| SCHEMBL31520096 | 0.83 | ALDH1A1 (0.63) | TSHRSMN1; SMN2ABCB1CYP4F2CYP4A11 | |
| SCHEMBL6865172 | 0.83 | ALDH1A1 (0.63) | TSHRSMN1; SMN2ABCB1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865707-B2 | Cholesteryl ester transfer protein inhibitors | MERCK SHARP & DOHME CORP. (US) | 2014-10-21 | — | — | US | disclosed |
| EP-1973546-B1 | CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | MERCK SHARP & DOHME (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20090280977-A1 | PROCESS FOR PREPARING CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L (IT) | 2009-11-12 | — | — | US | disclosed |
| EP-2051999-A1 | PROCESS FOR PREPARING CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2009-04-29 | — | — | EP | disclosed |
| US-20090018054-A1 | Cholesteryl Ester Transfer Protein Inhibitors | MERCK SHARP & DOHME LLC | 2009-01-15 | — | — | US | disclosed |
| EP-1973546-A2 | CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | Merck & Co., Inc. (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2008019802-A1 | PROCESS FOR PREPARING CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (DE) | 2008-02-21 | — | — | WO | disclosed |
| WO-2007081570-A2 | CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | MERCK & CO., INC. (US) | 2007-07-19 | — | — | WO | disclosed |
| EP-0849291-B1 | Catalyst for olefin polymerization and method for preparing polyolefins | JAPAN POLYOLEFINS CO LTD (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-6271167-B1 | TRIMETHOXYSILANE COMPOUND | JAPAN POLYOLEFINS CO., LTD. (JP) | 2001-08-07 | — | — | US | disclosed |
| EP-0849291-A1 | Catalyst for olefin polymerization and method for preparing polyolefins | Japan Polyolefins Co., Ltd. (JP) | 1998-06-24 | — | — | EP | disclosed |
| US-5693729-A | STEREOSPECIFIC CATALYZING IN PRESENCE OF A MIXTURE CONSISTING OF A TITANIUM AND A MAGNESIUM COMPOUND, AN ORGANOALUMINUM COMPOUND OR AN ALUMOXANE, AN ORGANOSILICON COMPOUND | SHOWA DENKO K.K. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0578473-B1 | Catalyst for polymerization of olefin and process for producing olefin polymer | SHOWA DENKO KK (JP) | 1997-11-19 | — | — | EP | disclosed |
| EP-0640624-B1 | Catalyst for polymerization of olefin and process for the preparation of olefin polymer | SHOWA DENKO KK (JP) | 1997-06-18 | — | — | EP | disclosed |
| EP-0717053-A2 | Catalyst for olefin polymerization and process for producing polyolefin using the same | JAPAN POLYOLEFINS CO., LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |
| EP-0704424-A1 | 3-alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1996-04-03 | — | — | EP | disclosed |
| US-5476825-A | Consists of magnesium, titanium and halogen compounds, an organoaluminum compound, a reaction product of organoaluminum or organoboron compound with organosilicon compound | SHOWA DENKO K.K. (JP) | 1995-12-19 | — | — | US | disclosed |
| US-5407883-A | Containing magnesium, titanium, aluminum and silicon compounds including polymeric aluminum and alumoxanes | SHOWA DENKO K.K. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0640624-A1 | Catalyst for polymerization of olefin and process for the preparation of olefin polymer | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1995-03-01 | — | — | EP | disclosed |
| EP-0578473-A1 | Catalyst for polymerization of olefin and process for producing olefin polymer | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1994-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018054-A1 | Cholesteryl Ester Transfer Protein Inhibitors | CETP, APOB, MTTP | CTNNB1 1467/4885WNT3A 1779/4885TSHR 4007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.