Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 2/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | VNN1 | O95497 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382984 | 0.84 | NAPRT (0.51) | KDM4EECE1NAPRTLMNAKMT2A | |
| SCHEMBL1827062 | 0.83 | KDM4E (0.63) | KDM4ENAPRTLMNAFDPSCHRM1 | |
| SCHEMBL12238430 | 0.83 | KDM4E (0.63) | KDM4ENAPRTLMNAFDPSCHRM1 | |
| SCHEMBL30186102 | 0.83 | KDM4E (0.63) | KDM4ENAPRTLMNAFDPSCHRM1 | |
| SCHEMBL5174680 | 0.83 | KDM4E (0.63) | KDM4ENAPRTLMNAFDPSCHRM1 | |
| SCHEMBL26065 | 0.83 | MDM2 (0.68) | LMNAKMT2ATDP1MDM2ALDH1A1 | |
| SCHEMBL27628032 | 0.82 | CHRM1 (0.60) | NAPRTLMNAKMT2ATDP1FDPS | |
| SCHEMBL11039118 | 0.81 | KDM4E (0.47) | KDM4EECE1NAPRTLMNAKMT2A | |
| SCHEMBL12906734 | 0.79 | FDPS (0.54) | KDM4ENAPRTLMNAKMT2AFDPS | |
| SCHEMBL6885074 | 0.76 | KDM4E (0.62) | KDM4ENAPRTLMNAFDPSCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118685-A | Antiarrhythmia agents | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |