Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 3/20 | 0.46 |
| ▸ | CPA3 | P15088 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29926764 | 0.87 | MDM2 (0.53) | MDM2CES2LMNACES1ALKBH5 | |
| SCHEMBL10988389 | 0.87 | MDM2 (0.53) | MDM2CES2CES1L3MBTL1MAPT | |
| SCHEMBL9748714 | 0.84 | MDM2 (0.50) | MDM2CYP1A2CTRB1TDP1L3MBTL1 | |
| SCHEMBL9748709 | 0.84 | MDM2 (0.50) | MDM2 | |
| SCHEMBL10830281 | 0.83 | CTSV (0.49) | MDM2LMNAALDH1A1KMT2A | |
| SCHEMBL10829586 | 0.83 | LDHA (0.58) | MDM2CYP1A2CES2CES1L3MBTL1 | |
| SCHEMBL10830284 | 0.83 | MDM2 (0.49) | MDM2ALDH1A1MAPTKMT2A | |
| SCHEMBL9737253 | 0.83 | KDM4E (0.53) | MDM2LMNATDP1ALDH1A1KMT2A | |
| SCHEMBL10829590 | 0.83 | PPARG (0.57) | MDM2CYP1A2CES2CES1ALDH1A1 | |
| SCHEMBL10830533 | 0.83 | ALDH1A1 (0.56) | MDM2LMNAL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480157-A | O-carborane derivative for assisting BNCT and synthetic method thereof | 南京艾斯特医药科技有限公司 | 2021-03-12 | — | — | CN | claimed |
| CN-108084002-A | A kind of preparation method of 2- hydroxy phenyls propiophenone | 常州瑞明药业有限公司 | 2018-05-29 | — | — | CN | claimed |
| EP-0123838-B1 | AMINOPROPANOL DERIVATIVES OF 1-(2-HYDROXYPHENYL)-3-PHENYL PROPANOLS, METHOD FOR THEIR MANUFACTURE AND THERAPEUTIC AGENTS CONTAINING THESE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1986-01-22 | — | — | EP | claimed |
| CN-112480157-B | O-carborane derivative for assisting BNCT and synthetic method thereof | 淮南科威生物科技有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-112480157-B | O-carborane derivative for assisting BNCT and synthetic method thereof | 淮南科威生物科技有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-112480157-A | O-carborane derivative for assisting BNCT and synthetic method thereof | 南京艾斯特医药科技有限公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-112480157-A | O-carborane derivative for assisting BNCT and synthetic method thereof | 南京艾斯特医药科技有限公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-105338815-B | Wipes with guanidino-containing polymers | 3M创新有限公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-108084002-A | A kind of preparation method of 2- hydroxy phenyls propiophenone | 常州瑞明药业有限公司 | 2018-05-29 | — | — | CN | disclosed |
| CN-108084002-A | A kind of preparation method of 2- hydroxy phenyls propiophenone | 常州瑞明药业有限公司 | 2018-05-29 | — | — | CN | disclosed |
| US-9445606-B2 | Use of 4-hydroxydihydrochalcones and their salts for enhancing an impression of sweetness | SYMRISE AG (DE) | 2016-09-20 | — | — | US | disclosed |
| US-4540697-A | ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| US-4540697-A | ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| US-4474986-A | Preparation of propafenone | BASF AKTIENGESELLSCHAFT (DE) | 1984-10-02 | — | — | US | disclosed |
| US-4460605-A | ANTIARRHYTHMIA AGENTS | HELOPHARM W. PETRIK & CO. (DE) | 1984-07-17 | — | — | US | disclosed |
| EP-0074014-B1 | 2-(2'-HYDROXY-3'-(1,1,-DIMETHYL PROPYLAMINO)-PROPOXY)-BETA PROPIOPHENONE, ITS ADDITION SALTS, PROCESS FOR ITS PREPARATION AND MEDICAMENTS | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1984-06-27 | — | — | EP | disclosed |
| EP-0075207-A2 | Aminopropanol derivatives of 2-hydroxy-beta-phenyl propiophenones, processes for their preparation and therapeutic agents containing them | BASF Aktiengesellschaft (DE) | 1983-03-30 | — | — | EP | disclosed |
| EP-0075207-A2 | Aminopropanol derivatives of 2-hydroxy-beta-phenyl propiophenones, processes for their preparation and therapeutic agents containing them | BASF Aktiengesellschaft (DE) | 1983-03-30 | — | — | EP | disclosed |
| WO-1983000688-A1 | 2-AD2'-HYDROXY-3'-(1,1-DIMETHYLPROPYLAMINO)-PROPOXYBD-BETA-PHENYLPROPIOPHENONE, PREPARATION AND PHARMACEUTICAL COMPOSITIONS | HELOPHARM PETRIK CO KG (DE) | 1983-03-03 | — | — | WO | disclosed |
| US-4254155-A | Preparing neohesperidin dihydrochalcone sweetener composition | CHIMICASA GMBH (CH) | 1981-03-03 | — | — | US | disclosed |