Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29613273 | 0.85 | ALDH1A1 (0.71) | HSPA5TSHRALDH1A1TDP1HIF1A | |
| SCHEMBL584830 | 0.85 | ALDH1A1 (0.71) | HSPA5TSHRALDH1A1TDP1HIF1A | |
| SCHEMBL146742 | 0.83 | ALDH1A1 (0.68) | HSPA5TSHRALDH1A1TDP1HIF1A | |
| SCHEMBL982784 | 0.82 | TSHR (0.52) | HSPA5TSHRALDH1A1TDP1CYP2D6 | |
| SCHEMBL49745 | 0.80 | HSPA5 (1.00) | HSPA5TSHRALDH1A1TDP1KEAP1 | |
| SCHEMBL29357407 | 0.80 | HSPA5 (1.00) | HSPA5TSHRALDH1A1TDP1KEAP1 | |
| SCHEMBL986181 | 0.79 | TSHR (0.48) | HSPA5TSHRALDH1A1TDP1CYP2D6 | |
| SCHEMBL9752003 | 0.79 | HSPA5 (0.57) | HSPA5TSHRALDH1A1TDP1KEAP1 | |
| SCHEMBL22240432 | 0.78 | TSHR (0.43) | HSPA5TSHRALDH1A1TDP1KEAP1 | |
| SCHEMBL29839938 | 0.78 | HSPA5 (0.94) | HSPA5TSHRALDH1A1TDP1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130410-A | Condencing a bishydroxymethyl phenol with a reactive phenol in the absence of an aldehyde to form an alternating copolymer and reacting in the presence of an aromatic aldehyde | SHIPLEY COMPANY INC. (US) | 1992-07-14 | — | — | US | claimed |