Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PDE6D | O43924 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737277 | 1.00 | CFTR (0.43) | CFTRALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL9736666 | 0.81 | CFTR (0.46) | CFTRALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL9698004 | 0.80 | CFTR (0.50) | CFTRALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL9737748 | 0.77 | ALDH1A1 (0.41) | CFTRALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL9737058 | 0.76 | F11 (0.37) | ALDH1A1KDM4EHPGDFAAHHSD17B10 | |
| SCHEMBL9737053 | 0.76 | F11 (0.37) | ALDH1A1KDM4EHPGDFAAHHSD17B10 | |
| SCHEMBL18152788 | 0.73 | ALDH1A1 (0.61) | CFTRALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL18152817 | 0.72 | TNF (0.57) | CFTRALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL28111190 | 0.72 | CFTR (0.50) | CFTRALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL1927930 | 0.70 | CFTR (0.48) | CFTRALDH1A1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005148-A1 | IMIDAZOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATIONS | RHONE-POULENC RORER LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |