Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737417 | 1.00 | MME (0.47) | MMEMEN1CYP3A4HPGDKMT2A | |
| SCHEMBL6991984 | 0.79 | SMN1; SMN2 (0.47) | MEN1CYP3A4HPGDKMT2AKDM4E | |
| SCHEMBL9352755 | 0.77 | KMT2A (0.44) | MEN1CYP3A4HPGDKMT2AKDM4E | |
| SCHEMBL11875103 | 0.77 | MME (0.48) | MMEMEN1CYP3A4HPGDKMT2A | |
| SCHEMBL11875098 | 0.77 | MME (0.48) | MMEMEN1CYP3A4HPGDKMT2A | |
| SCHEMBL2791574 | 0.73 | CA2 (0.66) | MMEPTPN1CA2CA1 | |
| SCHEMBL2792747 | 0.73 | CA2 (0.66) | MMEPTPN1CA2CA1 | |
| SCHEMBL9943491 | 0.73 | CA2 (0.66) | MMEPTPN1CA2CA1 | |
| SCHEMBL9501070 | 0.70 | MEN1 (0.63) | MEN1KMT2ACA2CA1ALDH1A1 | |
| SCHEMBL11278571 | 0.70 | NR4A2 (0.46) | MEN1CYP3A4HPGDKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144043-A | Coupling protein or peptide to radionucleotide; labeling antibodies | CENTOCOR (US) | 1992-09-01 | — | — | US | disclosed |