Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.42 |
| ▸ | FEN1 | P39748 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9352755 | 0.85 | KMT2A (0.44) | SMN1; SMN2MAPTMEN1CYP3A4HPGD | |
| SCHEMBL9737417 | 0.79 | MME (0.47) | SMN1; SMN2MAPTMEN1CYP3A4HPGD | |
| SCHEMBL9737425 | 0.79 | MME (0.47) | SMN1; SMN2MAPTMEN1CYP3A4HPGD | |
| SCHEMBL6994495 | 0.79 | KMT2A (0.44) | SMN1; SMN2MAPTMEN1CYP3A4HPGD | |
| SCHEMBL6989814 | 0.77 | NR4A2 (0.42) | SMN1; SMN2MAPTMEN1CYP3A4HPGD | |
| SCHEMBL8596365 | 0.74 | MEN1 (0.57) | SMN1; SMN2MAPTMEN1CYP3A4HPGD | |
| SCHEMBL10505514 | 0.72 | GPR139 (0.41) | SMN1; SMN2MAPTMEN1CYP3A4HPGD | |
| SCHEMBL24130554 | 0.72 | NPC1 (0.57) | SMN1; SMN2PTPN1GAARAB9ANPC1 | |
| SCHEMBL24130553 | 0.72 | NPC1 (0.57) | SMN1; SMN2PTPN1GAARAB9ANPC1 | |
| SCHEMBL11285319 | 0.72 | MAPT (0.52) | SMN1; SMN2MAPTMEN1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606683-B1 | Means for diagnosis of angiogenic diseases | DIAGNOSTIKFORSCHUNG INST (DE) | 2003-01-02 | — | — | EP | claimed |
| EP-0606683-B1 | Means for diagnosis of angiogenic diseases | DIAGNOSTIKFORSCHUNG INST (DE) | 2003-01-02 | — | — | EP | disclosed |
| US-6342201-B1 | COMPLEXES WHICH ENRICH ARTERIOSCLEROTIC PLAQUE AND ARE PREFERENTIALLY SUITED FOR NON-INVASIVE DIAGNOSIS OF ARTERIOSCLEROSIS | INSTITUT FOR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT (DE) | 2002-01-29 | — | — | US | disclosed |
| EP-0772633-A1 | COMPLEXES FOR USE IN THE DIAGNOSIS OF VASCULAR DISEASES | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996002568-A1 | COMPLEXES FOR USE IN THE DIAGNOSIS OF VASCULAR DISEASES | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |
| EP-0606683-A2 | Means for diagnosis of angiogenic diseases | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 1994-07-20 | — | — | EP | disclosed |