Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 16/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9471998 | 0.88 | PIK3CD (0.51) | PIK3CDPIK3R1LTA4H | |
| SCHEMBL9626040 | 0.85 | PIK3CD (0.38) | PIK3CDPIK3R1LTA4HCYP1A2CYP2D6 | |
| SCHEMBL8307878 | 0.80 | HTT (0.54) | PIK3CDPIK3R1HTTMAPT | |
| SCHEMBL11109514 | 0.75 | PIK3CD (0.57) | PIK3CDPIK3R1 | |
| SCHEMBL17051142 | 0.74 | HTT (0.42) | HTTMAPT | |
| SCHEMBL15684755 | 0.74 | HTT (0.49) | L3MBTL1HTTMAPT | |
| SCHEMBL9185972 | 0.74 | CCNC (0.51) | CYP1A2HTT | |
| SCHEMBL28673572 | 0.74 | GAA (0.37) | PIK3CDPIK3R1CYP1A2HTT | |
| SCHEMBL29882152 | 0.74 | GAA (0.37) | PIK3CDPIK3R1CYP1A2HTT | |
| SCHEMBL11104537 | 0.74 | PIK3CD (0.56) | L3MBTL1PIK3CDPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4225963-A | — | — | None | — | — | JP | disclosed |
| JP-H04225963-A | AMINOPYRIMIDINE DERIVATIVE, ITS PRODUCTION AND USE | NIPPON NOHYAKU CO LTD | 1992-08-14 | — | — | JP | disclosed |
| EP-0453137-A2 | Aminopyrimidine derivatives, a process for production thereof, and uses thereof | NIHON NOHYAKU CO., LTD. (JP) | 1991-10-23 | — | — | EP | disclosed |