Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737429 | 0.85 | L3MBTL1 (0.47) | PIK3CDPIK3R1LTA4HMAPTCYP1A2 | |
| SCHEMBL10434916 | 0.84 | TP53 (0.36) | EGFRERBB2KDM4EMEN1KMT2A | |
| SCHEMBL11280715 | 0.81 | MAPT (0.38) | EGFRERBB2KDM4EMEN1KMT2A | |
| SCHEMBL11107034 | 0.79 | PDE5A (0.38) | PIK3CDPIK3R1EGFRERBB2KDM4E | |
| SCHEMBL9450884 | 0.78 | LTA4H (0.38) | EGFRERBB2KDM4EMEN1KMT2A | |
| SCHEMBL11285261 | 0.78 | SMN1; SMN2 (0.37) | KDM4EMEN1KMT2AMAPK1APP | |
| SCHEMBL11281476 | 0.78 | S1PR2 (0.39) | KDM4EMEN1KMT2AMAPK1APP | |
| SCHEMBL10378449 | 0.77 | TP53 (0.36) | KDM4EMEN1KMT2AMAPK1APP | |
| SCHEMBL11108006 | 0.75 | MAPT (0.39) | KDM4EMEN1KMT2AMAPK1PDE5A | |
| SCHEMBL11289412 | 0.75 | SMN1; SMN2 (0.40) | KDM4EKMT2AMAPK1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467760-A1 | Pyrimidine derivatives, methods for producing them, and fungicides, insecticides and/or acaricides containing them as active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0453137-A2 | Aminopyrimidine derivatives, a process for production thereof, and uses thereof | NIHON NOHYAKU CO., LTD. (JP) | 1991-10-23 | — | — | EP | disclosed |