Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 11/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417857 | 0.81 | NR1H4 (0.60) | NR1H4LTB4RLTB4R2ALDH1A1HPGD | |
| SCHEMBL6762699 | 0.79 | LTB4R (0.59) | NR1H4LTB4RLTB4R2ALDH1A1HPGD | |
| SCHEMBL9735250 | 0.75 | CNR2 (0.41) | CYSLTR2CYSLTR1 | |
| SCHEMBL9417910 | 0.75 | LTB4R (0.54) | NR1H4LTB4RLTB4R2ALDH1A1HPGD | |
| SCHEMBL10746606 | 0.74 | CYSLTR2 (0.61) | MEN1CYP3A4ALOX15TSHRKMT2A | |
| SCHEMBL8568441 | 0.72 | MAOB (0.54) | NR1H4MAOB | |
| SCHEMBL8653477 | 0.71 | LTB4R (0.58) | NR1H4LTB4RLTB4R2ALDH1A1HPGD | |
| SCHEMBL8650952 | 0.71 | LTB4R (0.59) | NR1H4LTB4RLTB4R2ALDH1A1HPGD | |
| SCHEMBL8653050 | 0.71 | LTB4R (0.58) | NR1H4LTB4RLTB4R2ALDH1A1HPGD | |
| SCHEMBL8652811 | 0.70 | LTB4R (0.60) | NR1H4LTB4RLTB4R2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098613-A | Aromatic ethers for treatment of mammals | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |