Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.41 |
| ▸ | CNR1 | P21554 | 14/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.37 |
| ▸ | PDE1A | P54750 | 2/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417752 | 0.79 | LTB4R (0.53) | PDE5APDE1APDE1BPDE1C | |
| SCHEMBL9737478 | 0.75 | NR1H4 (0.40) | CYSLTR2CYSLTR1 | |
| SCHEMBL9735490 | 0.68 | TSHR (0.37) | CYSLTR2CYSLTR1 | |
| SCHEMBL9737643 | 0.68 | MRGPRX4 (0.58) | PDE5A | |
| SCHEMBL19143608 | 0.65 | KDM4E (0.49) | TRPV1 | |
| SCHEMBL28811440 | 0.65 | ALB (0.50) | CNR2CNR1CYSLTR2CYSLTR1 | |
| SCHEMBL9417862 | 0.64 | PDE5A (0.60) | CYSLTR2CYSLTR1PDE5APDE1APDE1B | |
| SCHEMBL13165911 | 0.63 | THRA (0.49) | CNR2CNR1 | |
| SCHEMBL12333287 | 0.62 | HDAC3 (0.55) | — | |
| SCHEMBL6159056 | 0.62 | HDAC3 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098613-A | Aromatic ethers for treatment of mammals | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |