Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.59 |
| ▸ | RELA | Q04206 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341780 | 0.92 | LMNA (0.56) | NR5A1LMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL10596404 | 0.92 | NPC1 (0.61) | LMNANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9152639 | 0.92 | NPC1 (0.61) | LMNANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9744741 | 0.91 | LMNA (0.58) | NR5A1LMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL9737680 | 0.89 | TP53 (0.54) | NR5A1LMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL9650301 | 0.89 | LMNA (0.72) | NR5A1LMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL9744746 | 0.89 | LMNA (0.72) | NR5A1LMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL11315675 | 0.89 | LMNA (0.72) | NR5A1LMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL8943247 | 0.89 | LMNA (0.72) | NR5A1LMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL9737668 | 0.89 | LMNA (0.72) | NR5A1LMNANPC1SMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098599-A | Aromatic esters with sulfide groups as liquid crystals | MITSUBISHI RAYON COMPANY LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0354355-A1 | Optically active compound and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |