Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.72 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.72 |
| ▸ | RELA | Q04206 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | LTA4H | P09960 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | ACR | P10323 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647625 | 1.00 | LMNA (0.72) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL1532142 | 1.00 | LMNA (0.72) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL5482347 | 1.00 | LMNA (0.72) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL5185777 | 1.00 | LMNA (0.72) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9650301 | 1.00 | LMNA (0.72) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL11315675 | 1.00 | LMNA (0.72) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL8943247 | 1.00 | LMNA (0.72) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9737668 | 1.00 | LMNA (0.72) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL1934741 | 1.00 | LMNA (0.72) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL27974007 | 1.00 | LMNA (0.72) | LMNANPC1NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098599-A | Aromatic esters with sulfide groups as liquid crystals | MITSUBISHI RAYON COMPANY LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0354355-A1 | Optically active compound and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |