Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2498935 | 0.76 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1CTSLCTSBCTSS | |
| SCHEMBL1285759 | 0.74 | ALDH1A1 (0.51) | SIGMAR1SMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL7468837 | 0.74 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1AGTR2MAPTHPGD | |
| SCHEMBL7468842 | 0.74 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1AGTR2MAPTHPGD | |
| SCHEMBL23944461 | 0.74 | ALDH1A1 (0.55) | SIGMAR1SMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL3594428 | 0.72 | CYP2C19 (0.41) | ALDH1A1HTR2CMAPTRAB9ACYP2C19 | |
| SCHEMBL25901621 | 0.72 | ALDH1A1 (0.53) | SIGMAR1SMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL11568741 | 0.72 | ALDH1A1 (0.47) | SIGMAR1SMN1; SMN2ALDH1A1CTSLCTSB | |
| SCHEMBL2497087 | 0.71 | ALDH1A1 (0.40) | SIGMAR1SMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL8615968 | 0.71 | ALDH1A1 (0.47) | SIGMAR1SMN1; SMN2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130307-A | Antibody inhibitors; treating organ graft rejection, fungal infections; antiinflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |