Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25901621 | 0.88 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTHPGDTDP1 | |
| SCHEMBL1285759 | 0.87 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTHPGDTDP1 | |
| SCHEMBL4450501 | 0.86 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTHPGDTDP1 | |
| SCHEMBL22326382 | 0.85 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTHPGDTDP1 | |
| SCHEMBL22780788 | 0.85 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTHPGDTDP1 | |
| SCHEMBL13397665 | 0.84 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTHPGDTDP1 | |
| SCHEMBL13300890 | 0.84 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTHPGDTDP1 | |
| SCHEMBL2188086 | 0.83 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTHPGDTDP1 | |
| SCHEMBL8615968 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTHPGDTDP1 | |
| SCHEMBL25178599 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4047012-A1 | ANTIMICROBIAL CATIONIC PEPTOID AND N-SUBTITUTED PEPTIDIC COPOLYMERS, PREPARATION AND USES THEREOF | Université de Bordeaux (FR) | 2022-08-24 | — | — | EP | disclosed |
| US-20210323913-A1 | SIGMA RECEPTOR BINDERS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2021-10-21 | — | — | US | disclosed |
| CN-1449380-A | Phenoxybenzylamine derivatives as selective serotonin re-uptake inhibitors | PFIZER LTD (US) | 2003-10-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323913-A1 | SIGMA RECEPTOR BINDERS | SIGMAR1, OPRK1, OPRL1 | ALDH1A1 431/4885SMN1; SMN2 715/4885MAPT 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.