Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736158 | 0.89 | PTGS2 (0.43) | TSHRPTGS2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9737054 | 0.86 | PTGS2 (0.56) | PTGS2ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL9521448 | 0.77 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL27447718 | 0.77 | BRD4 (0.47) | PTGS2BRD4SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL14513801 | 0.69 | PTGS2 (0.53) | TSHRPTGS2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8430909 | 0.69 | TSHR (0.49) | TSHRPTGS2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9323989 | 0.69 | TSHR (0.49) | TSHRSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL9876240 | 0.69 | KDM4E (0.38) | TSHRSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL15033450 | 0.67 | TSHR (0.47) | TSHRSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL7513475 | 0.67 | TSHR (0.47) | TSHRPTGS2SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007835-A1 | IMIDAZOLE FUNGICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-05-14 | — | — | WO | disclosed |