Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PRKX | P51817 | 1/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520829 | 0.90 | PTGS2 (0.39) | TSHRSMN1; SMN2HPGDNPSR1ALDH1A1 | |
| SCHEMBL932694 | 0.88 | KMT2A (0.38) | TSHRSMN1; SMN2HPGDNPSR1ALDH1A1 | |
| SCHEMBL933896 | 0.86 | ADORA1 (0.42) | TSHRSMN1; SMN2HPGDALDH1A1NPC1 | |
| SCHEMBL933331 | 0.85 | TSHR (0.34) | TSHRSMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL8430909 | 0.82 | TSHR (0.49) | TSHRSMN1; SMN2HPGDNPSR1ALDH1A1 | |
| SCHEMBL932277 | 0.78 | PTGS2 (0.39) | TSHRHPGDPDGFRBPDGFRAALDH1A1 | |
| SCHEMBL9519745 | 0.77 | SMN1; SMN2 (0.33) | SMN1; SMN2KDM4E | |
| SCHEMBL8309018 | 0.75 | MAPT (0.43) | TSHRSMN1; SMN2HPGDNPSR1ALDH1A1 | |
| SCHEMBL8310433 | 0.74 | HTT (0.43) | TSHRHPGDNPSR1ALDH1A1KDM4E | |
| SCHEMBL9521448 | 0.74 | TSHR (0.46) | TSHRSMN1; SMN2HPGDNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365030-B1 | Imidazole compound and process for preparing the same | ISHIHARA SANGYO KAISHA (JP) | 1994-01-26 | — | — | EP | disclosed |
| EP-0298196-B1 | IMIDAZOLE COMPOUNDS AND BIOCIDAL COMPOSITIONS COMPRISING THE SAME | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1993-06-02 | — | — | EP | disclosed |
| EP-0337103-B1 | BIOCIDAL COMPOSITION | ISHIHARA SANGYO KAISHA, Ltd. (JP) | 1993-02-10 | — | — | EP | disclosed |
| US-5023336-A | Fungicides, biocides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1991-06-11 | — | — | US | disclosed |
| US-4995898-A | Imidazole compounds and biocidal composition comprising the same for controlling harmful organisms | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1991-02-26 | — | — | US | disclosed |
| EP-0365030-A1 | Imidazole compound and process for preparing the same | ISHIHARA SANGYO KAISHA, Ltd. (JP) | 1990-04-25 | — | — | EP | disclosed |
| EP-0337103-A2 | Biocidal composition | ISHIHARA SANGYO KAISHA, Ltd. (JP) | 1989-10-18 | — | — | EP | disclosed |
| EP-0298196-A1 | Imidazole compounds and biocidal compositions comprising the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1989-01-11 | — | — | EP | disclosed |