Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 5/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737739 | 1.00 | KDM4E (0.50) | KDM4EHIF1ALMNANR3C1CYP3A4 | |
| SCHEMBL9737736 | 1.00 | KDM4E (0.50) | KDM4EHIF1ALMNANR3C1CYP3A4 | |
| SCHEMBL9738019 | 0.88 | KDM4E (0.57) | KDM4EHIF1ALMNANR3C1CYP3A4 | |
| SCHEMBL9738025 | 0.88 | KDM4E (0.57) | KDM4EHIF1ALMNANR3C1CYP3A4 | |
| SCHEMBL9738022 | 0.88 | KDM4E (0.57) | KDM4EHIF1ALMNANR3C1CYP3A4 | |
| SCHEMBL9738151 | 0.84 | ALDH1A1 (0.50) | HIF1ALMNANR3C1CYP3A4SMN1; SMN2 | |
| SCHEMBL9738161 | 0.84 | ALDH1A1 (0.50) | HIF1ALMNANR3C1CYP3A4SMN1; SMN2 | |
| SCHEMBL9738157 | 0.84 | ALDH1A1 (0.50) | HIF1ALMNANR3C1CYP3A4SMN1; SMN2 | |
| SCHEMBL9737529 | 0.81 | KDM4E (0.50) | KDM4EHIF1ALMNANR3C1CYP3A4 | |
| SCHEMBL11325098 | 0.79 | HIF1A (0.55) | KDM4EHIF1ALMNANR3C1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278319-B1 | 9,11-EPOXY-21-HYDROXYPREGNANE DERIVATIVES | THE UPJOHN COMPANY (US) | 1992-10-07 | — | — | EP | claimed |