Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 10/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.42 |
| ▸ | PGR | P06401 | 5/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738025 | 1.00 | KDM4E (0.57) | KDM4EHIF1ACYP3A4LMNANR3C1 | |
| SCHEMBL9738019 | 1.00 | KDM4E (0.57) | KDM4EHIF1ACYP3A4LMNANR3C1 | |
| SCHEMBL9737736 | 0.88 | KDM4E (0.50) | KDM4EHIF1ACYP3A4LMNANR3C1 | |
| SCHEMBL9737739 | 0.88 | KDM4E (0.50) | KDM4EHIF1ACYP3A4LMNANR3C1 | |
| SCHEMBL9737729 | 0.88 | KDM4E (0.50) | KDM4EHIF1ACYP3A4LMNANR3C1 | |
| SCHEMBL9522320 | 0.84 | KDM4E (0.60) | KDM4EHIF1ACYP3A4LMNANR3C1 | |
| SCHEMBL9522316 | 0.84 | KDM4E (0.60) | KDM4EHIF1ACYP3A4LMNANR3C1 | |
| SCHEMBL9522326 | 0.84 | KDM4E (0.60) | KDM4EHIF1ACYP3A4LMNANR3C1 | |
| SCHEMBL9737529 | 0.84 | KDM4E (0.50) | KDM4EHIF1ACYP3A4LMNANR3C1 | |
| SCHEMBL9736760 | 0.82 | ALDH1A1 (0.57) | KDM4EHIF1ACYP3A4LMNANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278319-B1 | 9,11-EPOXY-21-HYDROXYPREGNANE DERIVATIVES | THE UPJOHN COMPANY (US) | 1992-10-07 | — | — | EP | claimed |