Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.48 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.48 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8178136 | 0.91 | GCGR (0.64) | GCGRGAAPOLBHTTALDH1A1 | |
| SCHEMBL13482768 | 0.91 | GCGR (0.64) | GCGRGAAPOLBHTTALDH1A1 | |
| SCHEMBL2648212 | 0.89 | GCGR (0.62) | GCGRGAAPOLBHTTALDH1A1 | |
| SCHEMBL9152067 | 0.89 | GCGR (0.61) | GCGRGAAPOLBHTTALDH1A1 | |
| SCHEMBL3192181 | 0.89 | GCGR (0.61) | GCGRGAAPOLBHTTALDH1A1 | |
| SCHEMBL8949663 | 0.87 | GCGR (0.61) | GCGRGAAPOLBHTTALDH1A1 | |
| SCHEMBL6565362 | 0.85 | GCGR (0.79) | GCGRSMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL5102023 | 0.84 | GCGR (0.56) | GCGRGAAPOLBHTTALDH1A1 | |
| SCHEMBL2649345 | 0.84 | GCGR (0.67) | GCGRGAAPOLBHTTALDH1A1 | |
| SCHEMBL5101638 | 0.84 | GCGR (0.58) | GCGRGAAPOLBHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173495-A | 7-[(2,6-dialkyl-4-furyl or thienyl-pyridyl)]-3,5-di-(dihydroxy-6-enoates) useful for treating circulatory diseases | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-22 | — | — | US | disclosed |
| US-5006530-A | Certain 7-[2,6-diisopropyl-4-phenyl-5-lower alkoxymethyl-pyrid-3-yl]-3,5-dihydroxy-6-enoates and derivatives useful for treating circulatory diseases | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |