Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737768 | 0.91 | GCGR (0.64) | GCGRTP53GAAPOLBSLC10A2 | |
| SCHEMBL13482768 | 0.91 | GCGR (0.64) | GCGRTP53GAAPOLBSLC10A2 | |
| SCHEMBL2648212 | 0.89 | GCGR (0.62) | GCGRGAAPOLBSLC10A2HTT | |
| SCHEMBL9152067 | 0.89 | GCGR (0.61) | GCGRTP53GAAPOLBSLC10A2 | |
| SCHEMBL3192181 | 0.89 | GCGR (0.61) | GCGRTP53GAAPOLBSLC10A2 | |
| SCHEMBL6565362 | 0.85 | GCGR (0.79) | GCGRNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL5102023 | 0.84 | GCGR (0.56) | GCGRTP53GAAPOLBSLC10A2 | |
| SCHEMBL6949795 | 0.84 | ADORA3 (0.50) | GCGRTP53GAAPOLBHTT | |
| SCHEMBL5101638 | 0.84 | GCGR (0.58) | GCGRTP53GAAPOLBSLC10A2 | |
| SCHEMBL5095166 | 0.84 | GCGR (0.55) | GCGRTP53GAAPOLBSLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127383-A | TREATMENT OF ARTERIOSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-03 | — | — | US | disclosed |
| US-5925645-A | ARTERIOSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-07-20 | — | — | US | disclosed |