Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LSS | P48449 | 9/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739233 | 0.83 | HTT (0.48) | HTTGAALSSL3MBTL1ALDH1A1 | |
| SCHEMBL9733196 | 0.80 | GAA (0.43) | HTTGAALSSL3MBTL1ALDH1A1 | |
| SCHEMBL24404988 | 0.68 | L3MBTL1 (0.46) | HTTGAALSSL3MBTL1ALDH1A1 | |
| SCHEMBL9152612 | 0.67 | HTT (0.64) | HTTL3MBTL1ALDH1A1PLA2G4BTP53 | |
| SCHEMBL9147535 | 0.67 | MAPT (0.59) | HTTGAALSSL3MBTL1ALDH1A1 | |
| SCHEMBL2405032 | 0.66 | CYP2C19 (0.50) | HTTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL10984865 | 0.66 | TP53 (0.69) | GAAPLA2G4BTP53TSHR | |
| SCHEMBL11137907 | 0.65 | TDP1 (0.57) | L3MBTL1ALDH1A1TP53LMNA | |
| SCHEMBL9152817 | 0.65 | HTT (0.61) | HTTL3MBTL1ALDH1A1PLA2G4BTP53 | |
| SCHEMBL13754154 | 0.65 | TP53 (0.55) | L3MBTL1ALDH1A1PLA2G4BTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098613-A | Aromatic ethers for treatment of mammals | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |