Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733196 | 0.84 | GAA (0.43) | HTTL3MBTL1ALDH1A1LSSGAA | |
| SCHEMBL9737799 | 0.83 | HTT (0.43) | HTTL3MBTL1ALDH1A1LSSGAA | |
| SCHEMBL9733516 | 0.77 | L3MBTL1 (0.47) | HTTL3MBTL1GAATP53TSHR | |
| SCHEMBL1334865 | 0.74 | GAA (0.61) | L3MBTL1LSSGAATP53TSHR | |
| SCHEMBL16414705 | 0.74 | GAA (0.61) | L3MBTL1LSSGAATP53TSHR | |
| SCHEMBL9772848 | 0.73 | CHRNB2 (0.51) | HTTL3MBTL1ALDH1A1GAA | |
| SCHEMBL5477923 | 0.73 | TP53 (0.72) | HTTL3MBTL1ALDH1A1GAATP53 | |
| SCHEMBL21183209 | 0.73 | CHRNB2 (0.51) | HTTL3MBTL1ALDH1A1GAA | |
| SCHEMBL9666009 | 0.73 | TP53 (0.72) | HTTL3MBTL1ALDH1A1GAATP53 | |
| SCHEMBL303109 | 0.73 | TP53 (0.72) | HTTL3MBTL1ALDH1A1GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098613-A | Aromatic ethers for treatment of mammals | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |