Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.35 |
| ▸ | PTPRA | P18433 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1209089 | 0.77 | CYP1A2 (0.51) | FFAR1MEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL25152686 | 0.77 | CYP1A2 (0.51) | FFAR1MEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL28659666 | 0.77 | PTPRA (0.39) | ALDH1A1CYP1A2KDM4EMAPTPTPRA | |
| SCHEMBL22092259 | 0.76 | LMNA (0.45) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL16151353 | 0.75 | KMT2A (0.40) | KMT2AALDH1A1CYP1A2KDM4EMAPT | |
| SCHEMBL25152913 | 0.74 | CYP2D6 (0.39) | ALDH1A1TSHRCYP1A2KDM4E | |
| SCHEMBL17061189 | 0.73 | CTSA (0.45) | FFAR1CYP1A2KDM4EMAPTFFAR4 | |
| SCHEMBL453189 | 0.73 | HDAC8 (0.33) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL453190 | 0.73 | TRPA1 (0.34) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL20472673 | 0.73 | TRPA1 (0.34) | MEN1NPC1RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162550-A | BISPHTHALIDE LACTONES, THEIR PREPARATION AND THE USE THEREOF IN RECORDING MATERIALS | CIBA-GEIGY CORPORATION (US) | 1992-11-10 | — | — | US | disclosed |