Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29106359 | 0.82 | LMNA (0.37) | TSHRCYP3A4LMNAKDM4ECYP2C9 | |
| SCHEMBL27918054 | 0.80 | TSHR (0.38) | TSHRLMNASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL27918052 | 0.80 | TSHR (0.38) | TSHRLMNASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL21742338 | 0.79 | TSHR (0.54) | TSHRCYP3A4LMNAKDM4EABCB11 | |
| SCHEMBL6587706 | 0.78 | TSHR (0.33) | TSHRCYP3A4LMNAKDM4EABCB11 | |
| SCHEMBL6294559 | 0.77 | PANK3 (0.34) | TSHRCYP3A4LMNAKDM4EABCB11 | |
| SCHEMBL6294563 | 0.77 | PANK3 (0.34) | TSHRCYP3A4LMNAKDM4EABCB11 | |
| SCHEMBL25272244 | 0.72 | ACACB (0.39) | TSHRCYP3A4LMNAKDM4EABCB11 | |
| SCHEMBL30489321 | 0.72 | ACACB (0.39) | TSHRCYP3A4LMNAKDM4EABCB11 | |
| SCHEMBL25272245 | 0.72 | ACACB (0.39) | TSHRCYP3A4LMNAKDM4EABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162550-A | BISPHTHALIDE LACTONES, THEIR PREPARATION AND THE USE THEREOF IN RECORDING MATERIALS | CIBA-GEIGY CORPORATION (US) | 1992-11-10 | — | — | US | disclosed |