Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA7 | P43166 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | DEGS1 | O15121 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918054 | 1.00 | TSHR (0.38) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL9737863 | 0.80 | TSHR (0.41) | TSHRPOLBMAPTCYP1A2LMNA | |
| SCHEMBL27936564 | 0.75 | P4HTM (0.50) | LMNA | |
| SCHEMBL27936565 | 0.75 | P4HTM (0.50) | LMNA | |
| SCHEMBL6587706 | 0.72 | TSHR (0.33) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL8994058 | 0.69 | APLNR (0.39) | APLNRDEGS1 | |
| SCHEMBL29111130 | 0.68 | ESR1 (0.48) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL17044891 | 0.68 | APLNR (0.43) | APLNR | |
| SCHEMBL6294559 | 0.67 | PANK3 (0.34) | TSHRPOLBMAPTMEN1KMT2A | |
| SCHEMBL6294563 | 0.67 | PANK3 (0.34) | TSHRPOLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304488-A | Preparation method of optical pure 2-(1-hydroxylethyl)-5-hydroxylpyrimidine | AGNO PHARMA TECH SZ LTD | 2013-09-18 | — | — | CN | disclosed |