Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9230330 | 1.00 | CA2 (0.52) | CA2MAPK1ACE2CA1MAPT | |
| Bicarbonate SCHEMBL885152 | 0.98 | CA2 (0.54) | CA2MAPK1ACE2CA1MAPT | |
| Bicarbonate SCHEMBL28895715 | 0.98 | CA2 (0.54) | CA2MAPK1ACE2CA1MAPT | |
| Bicarbonate SCHEMBL28584877 | 0.98 | CA2 (0.54) | CA2MAPK1ACE2CA1MAPT | |
| Bicarbonate SCHEMBL216624 | 0.98 | CA2 (0.54) | CA2MAPK1ACE2CA1MAPT | |
| Acetic Acid SCHEMBL4207526 | 0.91 | CA2 (0.52) | CA2MAPK1ACE2CA1MAPT | |
| Propionic Acid SCHEMBL28527697 | 0.88 | CA2 (0.50) | CA2MAPK1ACE2CA1MAPT | |
| Acetic Acid SCHEMBL9623423 | 0.88 | ACE2 (0.53) | CA2MAPK1ACE2CA1MAPT | |
| Acetic Acid SCHEMBL7095795 | 0.88 | CA2 (0.50) | CA2MAPK1ACE2CA1MAPT | |
| Bicarbonate SCHEMBL18274643 | 0.88 | ACE2 (0.64) | CA2ACE2CA1MAPTGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906569-B1 | HYDROSILYLATION SYNTHESIS OF HALOALKYLORGANOSILANES USING PEROXIDE PROMOTERS | MOMENTIVE PERFORMANCE MAT INC (US) | 2018-06-13 | — | — | EP | claimed |
| EP-4682227-A1 | NOVEL DIESEL FUEL ADDITIVE PACKAGES | BASF SE (DE) | 2026-01-21 | — | — | EP | disclosed |
| US-20240392053-A1 | THERMOSETTING COMPOSITIONS BASED ON (METH)ACRYLATES AND PEROXODICARBONATES | DELO INDUSTRIE KLEBSTOFFE GMBH & CO. KGAA (DE) | 2024-11-28 | — | — | US | disclosed |
| US-12060480-B2 | Polymer compositions and use thereof as pour point depressants in paraffin-containing hydrocarbon oils | CLARIANT INTERNATIONAL LTD (CH) | 2024-08-13 | — | — | US | disclosed |
| US-11993550-B2 | Water resistance additive for particulate ammonium nitrate-fuel oil (ANFO) explosives | CLARIANT INTERNATIONAL LTD (CH) | 2024-05-28 | — | — | US | disclosed |
| US-11981876-B2 | Wax inhibitors with improved flowability | CLARIANT INTERNATIONAL LTD (CH) | 2024-05-14 | — | — | US | disclosed |
| US-11976248-B2 | Dispersions of polymeric oil additives | DORF KETAL ENERGY SERVICES LLC (US) | 2024-05-07 | — | — | US | disclosed |
| EP-3448832-B1 | WATER RESISTANCE ADDITIVE FOR PARTICULATE AMMONIUM NITRATE-FUEL OIL (ANFO) EXPLOSIVES | CLARIANT INT LTD (CH) | 2023-08-02 | — | — | EP | disclosed |
| EP-4004142-B1 | WAX INHIBITORS WITH IMPROVED FLOWABILITY | CLARIANT INT LTD (CH) | 2023-06-07 | — | — | EP | disclosed |
| US-20220380590-A1 | Polymer compositions and use thereof as pour Point depressants in Paraffin-containing hydrocarbon oils | CLARIANT INTERNATIONAL LTD. (CH) | 2022-12-01 | — | — | US | disclosed |
| US-20010013196-A1 | Multifunctional additive for fuel oils | CLARIANT GMBH | 2001-08-16 | — | — | US | disclosed |
| US-6245410-B1 | PLASTICS | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-12 | — | — | US | disclosed |
| US-6174929-B1 | FOAMING AQUEOUS MIXTURE OF MONOETHYLENICALLY UNSATURATED MONOMERS CONTAINING ACID GROUPS, WHICH NEUTRALIZED, WITH OR WITHOUT MONOETHYLENICALLY UNSATURATED MONOMERS, CROSSLINKERS; SURFACTANTS, INITIATORS, DISPERSING GAS BUBBLES, POLYMERIZING | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-16 | — | — | US | disclosed |
| EP-0573037-B1 | Coating agent for coating aluminium | WACKER CHEMIE GMBH (DE) | 1997-02-26 | — | — | EP | disclosed |
| US-5525656-A | HEAT SEALABLE COMPOSITION CONSISTING OF VINYL ESTER COPOLYMER IN ORGANIC SOLVENT; HALOGEN-FREE | WACKER CHEMIE GMBH (DE) | 1996-06-11 | — | — | US | disclosed |
| EP-0467276-B1 | Polymer scale preventive agent and method of preventing polymer scale deposition using the same | SHINETSU CHEMICAL CO (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5430113-A | Coating polymerization vessel; product of condensation of amino- and nitro-aromatic compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| EP-0573037-A1 | Coating agent for coating aluminium | Wacker-Chemie GmbH (DE) | 1993-12-08 | — | — | EP | disclosed |
| US-5254652-A | Containing vinyl acetate and vinyl neononanoate or neodecanoate | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-19 | — | — | US | disclosed |
| EP-0467276-A2 | Polymer scale preventive agent and method of preventing polymer scale deposition using the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-01-22 | — | — | EP | disclosed |