SCHEMBL9738223

SCHEMBL9738223

C=CCOC(=O)N1C[C@@H](SC(C)=O)C[C@H]1C(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.42
MMP2 P08253 8/20 0.38
ANPEP P15144 4/20 0.38
ERN1 O75460 1/20 0.32
SIGMAR1 Q99720 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PEPD P12955 2/20 0.31
XPNPEP1 Q9NQW7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9130961 1.00 CYP19A1 (0.42) CYP19A1MMP2ANPEPERN1SIGMAR1
SCHEMBL5095282 0.88 ATM (0.34) CYP19A1SIGMAR1
SCHEMBL8786851 0.88 ATM (0.34) CYP19A1SIGMAR1
SCHEMBL5095470 0.88 ATM (0.34) CYP19A1SIGMAR1
SCHEMBL9132237 0.86 CYP19A1 (0.42) CYP19A1MMP2ANPEPERN1
SCHEMBL6399031 0.84 CYP19A1 (0.31) CYP19A1SIGMAR1
SCHEMBL8805757 0.82 SIGMAR1 (0.33) CYP19A1SIGMAR1
SCHEMBL8805750 0.82 SIGMAR1 (0.33) CYP19A1SIGMAR1
SCHEMBL9567186 0.82 FAAH (0.32) CYP19A1
SCHEMBL8545366 0.81 FABP7 (0.36) CYP19A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5095013-A Antibiotics BANYU PHARMACEUTICAL CO., LTD. (JP) 1992-03-10 US disclosed
EP-0411664-A2 2-(2-Vinylpyrrolidinylthio)carbapenem derivatives Banyu Pharmaceutical Co., Ltd. (JP) 1991-02-06 EP disclosed