Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA1 | Q92743 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | FAP | Q12884 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738245 | 1.00 | HTRA1 (0.36) | HTRA1ALDH1A1DPP4DPP7CYP3A4 | |
| SCHEMBL9738733 | 0.88 | HTRA1 (0.38) | HTRA1ALDH1A1DPP4DPP7CYP3A4 | |
| SCHEMBL9737498 | 0.82 | CYP19A1 (0.42) | HTRA1ALDH1A1DPP4DPP7CYP3A4 | |
| SCHEMBL9738363 | 0.81 | HTRA1 (0.37) | HTRA1ALDH1A1DPP4DPP7CYP3A4 | |
| SCHEMBL9737552 | 0.73 | SIGMAR1 (0.33) | CYP19A1SIGMAR1 | |
| SCHEMBL9737546 | 0.73 | SIGMAR1 (0.33) | CYP19A1SIGMAR1 | |
| SCHEMBL5414235 | 0.73 | DPP4 (0.43) | HTRA1ALDH1A1DPP4DPP7MAPT | |
| SCHEMBL8545366 | 0.72 | FABP7 (0.36) | ALDH1A1MAPKAPK2CA1CA2TP53 | |
| SCHEMBL8095363 | 0.70 | GAA (0.44) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9202402 | 0.70 | HTRA1 (0.44) | HTRA1ALDH1A1DPP4DPP7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095013-A | Antibiotics | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-03-10 | — | — | US | disclosed |
| EP-0411664-A2 | 2-(2-Vinylpyrrolidinylthio)carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-02-06 | — | — | EP | disclosed |