Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | HTRA1 | Q92743 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738733 | 0.86 | HTRA1 (0.38) | HTRA1CYP3A4TP53TSHRMAPKAPK2 | |
| SCHEMBL9738363 | 0.85 | HTRA1 (0.37) | CYP19A1HTRA1CYP3A4TP53TSHR | |
| SCHEMBL5409683 | 0.84 | HTRA1 (0.46) | HTRA1CYP3A4ALDH1A1SMN1; SMN2MMP2 | |
| SCHEMBL9738245 | 0.82 | HTRA1 (0.36) | CYP19A1HTRA1CYP3A4TP53TSHR | |
| SCHEMBL9738251 | 0.82 | HTRA1 (0.36) | CYP19A1HTRA1CYP3A4TP53TSHR | |
| SCHEMBL8545366 | 0.81 | FABP7 (0.36) | CYP19A1TP53TSHRMAPKAPK2CA1 | |
| SCHEMBL9202881 | 0.77 | HTRA1 (0.42) | HTRA1ALDH1A1SMN1; SMN2HPGDDPP4 | |
| SCHEMBL6942572 | 0.77 | HTRA1 (0.42) | HTRA1ALDH1A1SMN1; SMN2HPGDDPP4 | |
| SCHEMBL8545707 | 0.77 | POLB (0.42) | CYP19A1CYP3A4TP53TSHRMAPKAPK2 | |
| SCHEMBL9738223 | 0.77 | CYP19A1 (0.42) | CYP19A1ALDH1A1MMP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095013-A | Antibiotics | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-03-10 | — | — | US | disclosed |
| EP-0411664-A2 | 2-(2-Vinylpyrrolidinylthio)carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-02-06 | — | — | EP | disclosed |