Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738262 | 1.00 | OPRM1 (0.39) | OPRM1MEN1KMT2AKDM4CCYP1A2 | |
| SCHEMBL17844772 | 0.86 | OPRM1 (0.52) | OPRM1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL17844735 | 0.86 | OPRM1 (0.52) | OPRM1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL7180161 | 0.84 | ALDH1A1 (0.40) | OPRM1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL7180157 | 0.84 | ALDH1A1 (0.40) | OPRM1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL31419830 | 0.81 | ALDH1A1 (0.50) | OPRM1MEN1KMT2AKDM4CALDH1A1 | |
| SCHEMBL25239721 | 0.81 | MEN1 (0.46) | OPRM1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL18160519 | 0.81 | MEN1 (0.38) | OPRM1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL18143737 | 0.81 | HPGD (0.47) | NPC1RAB9A | |
| SCHEMBL25239720 | 0.81 | MEN1 (0.46) | OPRM1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089635-A | Antiprogesterone, antiglucocorticoids | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| EP-0190759-B1 | 11-BETA PHENYL GONANES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-08-30 | — | — | EP | disclosed |
| EP-0190759-A2 | 11-Beta phenyl gonanes, their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-08-13 | — | — | EP | disclosed |