Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135563 | 1.00 | F2 (0.53) | F2PRSS1PRSS2PRSS3GAA | |
| SCHEMBL16042071 | 0.83 | F2 (0.50) | F2PRSS1PRSS2PRSS3GAA | |
| SCHEMBL17493464 | 0.79 | GAA (0.53) | F2PRSS1PRSS2PRSS3GAA | |
| SCHEMBL12377380 | 0.78 | GAA (0.52) | F2PRSS1PRSS2PRSS3GAA | |
| SCHEMBL5138891 | 0.78 | F2 (0.59) | F2PRSS1PRSS2PRSS3GAA | |
| SCHEMBL17137206 | 0.78 | KMT2A (0.51) | F2PRSS1PRSS2PRSS3GAA | |
| SCHEMBL18025298 | 0.78 | PKM (0.54) | GAACYP2C19HTTLMNAHPGD | |
| SCHEMBL9385131 | 0.77 | F2 (0.48) | F2PRSS1PRSS2PRSS3GAA | |
| SCHEMBL663730 | 0.76 | CYP2C19 (0.59) | F2PRSS1PRSS2PRSS3GAA | |
| SCHEMBL127246 | 0.76 | F2 (0.57) | F2PRSS1PRSS2PRSS3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134152-A | 1,2,4-Triazole compounds | SANKYO COMPANY, LIMITED (JP) | 1992-07-28 | — | — | US | disclosed |
| EP-0431968-A1 | Oxetane derivatives, their preparation and their use as anti-fungal or fungicidal agents | Sankyo Company Limited (JP) | 1991-06-12 | — | — | EP | disclosed |