Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | PTAFR | P25105 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9717955 | 0.99 | TSHR (0.50) | TSHRNAMPTPTAFRSMN1; SMN2L3MBTL1 | |
| SCHEMBL9717898 | 0.89 | PTAFR (0.45) | NAMPTPTAFR | |
| Hydrochloric Acid SCHEMBL9717927 | 0.88 | PTAFR (0.44) | NAMPTPTAFR | |
| SCHEMBL9717850 | 0.88 | TSHR (0.47) | TSHRNAMPTSMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL9646322 | 0.87 | PTAFR (0.47) | PTAFRL3MBTL1RAB9A | |
| SCHEMBL9717875 | 0.82 | NAMPT (0.45) | NAMPTPTAFRL3MBTL1RAB9A | |
| SCHEMBL9738331 | 0.78 | PTAFR (0.50) | PTAFR | |
| Hydrochloric Acid SCHEMBL9717958 | 0.78 | PTAFR (0.49) | PTAFR | |
| SCHEMBL9717904 | 0.76 | VNN1 (0.39) | NAMPTL3MBTL1 | |
| SCHEMBL9717971 | 0.76 | GRM2 (0.46) | TSHRPTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992019618-A1 | PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-11-12 | — | — | WO | disclosed |